My work can be probably defined as a convergence between chemistry and biology. In particular, I study the biochemical mechanisms leading to the progression of neurodegenerative disorders, such as Alzheimer's and Parkinson's diseases; these conditions are strongly associated with the presence of insoluble and fibrillar deposits generated by the aggregation of neuroproteins, in which the interaction with metal ions and reactive free species plays not negligible roles. Therefore, I focused my attention on the possible binding between neuronal proteins and metals, as iron or copper ions, assaying the reactivity of these adducts and the implications in the development of these pathological conditions.